Montgomery-Asberg Rating Scale (MADRS)

The Montgomery-Asberg Rating Scale (MADRS) is a 10-item clinician-rated assessment for depression in adults (18+). The MADRS focusses more upon functional impairment and somatic symptoms than other assessments which might focus more upon depressive cognitive attitudes (Montgomery and Asberg, 1979). 

 

Developer

Montgomery, S.A., & Asberg, M. (1979). A new depression scale designed to be sensitive to change. British Journal of Psychiatry, 134(4), 382–389. doi: 10.1192/bjp.134.4.382. PMID: 444788.

References

Carmody, T.J., Rush, A.J., Bernstein, I., Warden, D., Brannan, S., Burnham, D., et al. (2006). The Montgomery Äsberg and the Hamilton ratings of depression: a comparison of measures. European Journal of Neuropsychopharmacology, 16(8), 601–611. doi: 10.1016/j.euroneuro.2006.04.008. Epub 2006 Jun 12. PMID: 16769204; PMCID: PMC2151980.

Davidson, J., Turnbull, C.D., Strickland, R., Miller, R., & Graves, K. (1986). The Montgomery-Asberg Depression Scale: reliability and validity. Acta Psychiatry Scandinavica, 73(5), 544–548. doi: 10.1111/j.1600-0447.1986.tb02723.x. PMID: 3751660.

Fredriksen, K. J., Gjestad, R., Walby, F. A., Anda, L. G., Oedegaard, K. J., & Schoeyen, H. K. (2022). High Scores on the Montgomery-Åsberg Depression Rating Scale and Psychotic Symptoms Predict Suicide: A Prospective Cohort Study of Psychiatric Acute Ward Patients. The Journal of Clinical Psychiatry, 83(5), 41950. https://doi.org/10.4088/JCP.21m14018

Heo, M., Murphy, C.F., & Meyers, B.S. (2007). Relationship between the Hamilton Depression Rating Scale and the Montgomery-Åsberg Depression Rating Scale in depressed elderly: a meta-analysis. American Journal of Geriatric Psychiatry, 15(10), 899–905. doi: 10.1097/JGP.0b013e318098614e. PMID: 17911366.

Mulder, R.T., Joyce, P.R., & Frampton, C. (2003). Relationships among measures of treatment outcome in depressed patients. Journal of Affective Disorders, (1–3), 127–135. doi: 10.1016/s0165-0327(02)00080-0. PMID: 12943942.

Müller, M. J., Himmerich, H., Kienzle, B., & Szegedi, A. (2003). Differentiating moderate and severe depression using the Montgomery-Asberg depression rating scale (MADRS). Journal of Affective Disorders, 77(3), 255–260. https://doi.org/10.1016/s0165-0327(02)00120-9

Snaith, R., Harrop, F., Newby, D., & Teale, C. (1986). Grade Scores of the Montgomery—Åsberg Depression and the Clinical Anxiety Scales. British Journal of Psychiatry, 148(5), 599-601. doi:10.1192/bjp.148.5.599

Fredriksen, K. J., Gjestad, R., Walby, F. A., Anda, L. G., Oedegaard, K. J., & Schoeyen, H. K. (2022). High Scores on the Montgomery-Åsberg Depression Rating Scale and Psychotic Symptoms Predict Suicide: A Prospective Cohort Study of Psychiatric Acute Ward Patients. The Journal of Clinical Psychiatry, 83(5), 41950. https://doi.org/10.4088/JCP.21m14018

Thase, M. E., Harrington, A., Calabrese, J., Montgomery, S., Niu, X., & Patel, M. D. (2021). Evaluation of MADRS severity thresholds in patients with bipolar depression. Journal of Affective Disorders, 286, 58–63. https://doi.org/10.1016/j.jad.2021.02.043

Turkoz, I., Alphs, L., Singh, J., Jamieson, C., Daly, E., Shawi, M., Sheehan, J. J., Trivedi, M. H., & Rush, A. J. (2021). Clinically meaningful changes on depressive symptom measures and patient-reported outcomes in patients with treatment-resistant depression. Acta Psychiatrica Scandinavica, 143(3), 253–263. https://doi.org/10.1111/acps.13260